(Pro)renin receptor knockdown in the paraventricular nucleus of the hypothalamus attenuates hypertension development and AT(1) receptor-mediated calcium events

Activation of the brain renin-angiotensin system (RAS) is a pivotal step in the pathogenesis of hypertension. The paraventricular nucleus (PVN) of the hypothalamus is a critical part of the angiotensinergic sympatho-excitatory neuronal network involved in neural control of blood pressure and hyperte...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Souza, Lucas A. C., Worker, Caleb J., Li, Wencheng, Trebak, Fatima, Watkins, Trevor, Gayban, Ariana Julia B., Yamasaki, Evan, Cooper, Silvana G., Drumm, Bernard T., Feng, Yumei
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620680/
https://ncbi.nlm.nih.gov/pubmed/30925093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00780.2018
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