Irisin counteracts high glucose and fatty acid-induced cytotoxicity by preserving the AMPK-insulin receptor signaling axis in C2C12 myoblasts

Irisin, a newly identified myokine, is critical to modulating body metabolism and biological homeostasis. However, whether irisin protects the skeletal muscles against metabolic stresses remains unknown. In this study, we determine the effect of irisin on high glucose and fatty acid-induced damages...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Yano, Naohiro, Zhang, Ling, Wei, Dennis, Dubielecka, Patrycja M., Wei, Lei, Zhuang, Shougang, Zhu, Ping, Qin, Gangjian, Liu, Paul Y., Chin, Y. Eugene, Zhao, Ting C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272726/
https://ncbi.nlm.nih.gov/pubmed/32182124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00219.2019
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