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Oncogenic super-enhancer formation in tumorigenesis and its molecular mechanisms

Super-enhancers (SEs) consist of a cluster of many enhancers bound to a great number of transcription factors. They are critical cis-regulatory elements that determine the identity of various human cell types. During tumorigenesis, DNA mutations and indels, chromosomal rearrangements, three-dimensio...

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Publicat a:Exp Mol Med
Autors principals: Jia, Qunying, Chen, Shuhua, Tan, Yuan, Li, Yuejin, Tang, Faqing
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272638/
https://ncbi.nlm.nih.gov/pubmed/32382065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0428-7
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