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Super-enhancer function and its application in cancer targeted therapy

Recently, super-enhancers (SEs) have been identified as a unique type of transcriptional regulation involved in cancer development. SEs exhibit a size, high transcription factor density, and strong binding to the transcriptional machinery compared with typical enhancers. SEs play an essential role i...

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Pubblicato in:NPJ Precis Oncol
Autori principali: Tang, Faqing, Yang, Zongbei, Tan, Yuan, Li, Yuejin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016125/
https://ncbi.nlm.nih.gov/pubmed/32128448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-020-0108-z
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