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Prescribed Doses of CYP2D6-Metabolized Drugs and Hemodynamic Responses in Relation to CYP2D6 Genotype Among Older Patients Exposed to Polypharmacy

BACKGROUND: Many drugs with dose-dependent effects on hemodynamic variables are metabolized by cytochrome P450 2D6 (CYP2D6). The aim of this study was to compare prescribed dosages and hemodynamic responses of such drugs in relation to pharmacogenetic variability in CYP2D6 metabolism among patients...

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Detalhes bibliográficos
Publicado no:Drugs Aging
Main Authors: Romskaug, Rita, Wyller, Torgeir Bruun, Straand, Jørund, Kersten, Hege, Molden, Espen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272489/
https://ncbi.nlm.nih.gov/pubmed/32346827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40266-020-00763-0
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