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The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting

A large fraction of epigenetically silent heterochromatin is anchored to the nuclear periphery via ‘tethering proteins’ that function to bridge heterochromatin and the nuclear membrane or nuclear lamina. We previously identified a human tethering protein, PRR14, that binds heterochromatin through an...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Dunlevy, Kelly L., Medvedeva, Valentina, Wilson, Jade E., Hoque, Mohammed, Pellegrin, Trinity, Maynard, Adam, Kremp, Madison M., Wasserman, Jason S., Poleshko, Andrey, Katz, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272351/
https://ncbi.nlm.nih.gov/pubmed/32317397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.240416
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