The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast

The plant defensin HsAFP1 is characterized by broad-spectrum antifungal activity and induces apoptosis in Candida albicans. In this study, we performed a transcriptome analysis on C. albicans cultures treated with HsAFP1 to gain further insight in the antifungal mode of action of HsAFP1. Various gen...

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Veröffentlicht in:Biochim Biophys Acta Biomembr
Hauptverfasser: Struyfs, Caroline, Cools, Tanne L., Cremer, Kaat De, Sampaio-Marques, Belém, Ludovico, Paula, Wasko, Brian M., Kaeberlein, Matt, Cammue, Bruno P.A., Thevissen, Karin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272304/
https://ncbi.nlm.nih.gov/pubmed/32145284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2020.183255
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