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The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization

HsAFP1, a plant defensin isolated from coral bells (Heuchera sanguinea), is characterized by broad-spectrum antifungal activity. Previous studies indicated that HsAFP1 binds to specific fungal membrane components, which had hitherto not been identified, and induces mitochondrial dysfunction and cell...

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Vydáno v:Front Microbiol
Hlavní autoři: Cools, Tanne L., Vriens, Kim, Struyfs, Caroline, Verbandt, Sara, Ramada, Marcelo H. S., Brand, Guilherme D., Bloch, Carlos, Koch, Barbara, Traven, Ana, Drijfhout, Jan W., Demuyser, Liesbeth, Kucharíková, Soňa, Van Dijck, Patrick, Spasic, Dragana, Lammertyn, Jeroen, Cammue, Bruno P. A., Thevissen, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702387/
https://ncbi.nlm.nih.gov/pubmed/29209301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02295
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