The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization

HsAFP1, a plant defensin isolated from coral bells (Heuchera sanguinea), is characterized by broad-spectrum antifungal activity. Previous studies indicated that HsAFP1 binds to specific fungal membrane components, which had hitherto not been identified, and induces mitochondrial dysfunction and cell...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Cools, Tanne L., Vriens, Kim, Struyfs, Caroline, Verbandt, Sara, Ramada, Marcelo H. S., Brand, Guilherme D., Bloch, Carlos, Koch, Barbara, Traven, Ana, Drijfhout, Jan W., Demuyser, Liesbeth, Kucharíková, Soňa, Van Dijck, Patrick, Spasic, Dragana, Lammertyn, Jeroen, Cammue, Bruno P. A., Thevissen, Karin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702387/
https://ncbi.nlm.nih.gov/pubmed/29209301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02295
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