Pseudomonas aeruginosa utilizes host-derived itaconate to redirect its metabolism to promote biofilm formation

The bacterium Pseudomonas aeruginosa is especially pathogenic, often being associated with intractable pneumonia and high mortality. How P. aeruginosa avoids immune clearance and persists in the inflamed human airway remains poorly understood. In this study, we show that P. aeruginosa can exploit th...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Riquelme, Sebastián A., Liimatta, Kalle, Lung, Tania Wong Fok, Fields, Blanche, Ahn, Danielle, Chen, David, Lozano, Carmen, Saénz, Yolanda, Uhlemann, Anne-Catrin, Kahl, Barbara C., Britto, Clemente J., DiMango, Emily, Prince, Alice
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272298/
https://ncbi.nlm.nih.gov/pubmed/32428444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.04.017
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