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Targeting chromosomal architectural HMGB proteins could be the next frontier in cancer therapy

Chromatin-associated architectural proteins are part of a fundamental support system for cellular DNA-dependent processes and can maintain/modulate the efficiency of DNA replication, transcription, and DNA repair. Interestingly, prognostic outcomes of many cancer types have been linked with the expr...

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Publicat a:Cancer Res
Autors principals: Mukherjee, Anirban, Vasquez, Karen M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272294/
https://ncbi.nlm.nih.gov/pubmed/32152151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3066
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