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FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching

Fibroblast growth factors (FGFs) 9 and 10 are essential during the pseudoglandular stage of lung development. Mesothelium-produced FGF9 is principally responsible for mesenchymal growth, whereas epithelium-produced FGF9 and mesenchyme-produced FGF10 guide lung epithelial development, and loss of eit...

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Bibliografische gegevens
Gepubliceerd in:Sci Signal
Hoofdauteurs: Yin, Yongjun, Ornitz, David M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271816/
https://ncbi.nlm.nih.gov/pubmed/32127497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aay4353
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