GATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors

Encouraging clinical results using immune checkpoint therapies to target the PD-1 axis in a variety of cancer types have paved the way for new immune therapy trials in brain tumor patients. However, the molecular mechanisms that regulate expression of the PD-1 pathway ligands, PD-L1 and PD-L2, remai...

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Publicat a:Sci Rep
Autors principals: Fu, Yujie, Liu, Connor J., Kobayashi, Dale K., Johanns, Tanner M., Bowman-Kirigin, Jay A., Schaettler, Maximilian O., Mao, Diane D., Bender, Diane, Kelley, Diane G., Uppaluri, Ravindra, Bi, Wenya Linda, Dunn, Ian F., Tao, Yu, Luo, Jingqin, Kim, Albert H., Dunn, Gavin P.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271235/
https://ncbi.nlm.nih.gov/pubmed/32493985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65915-z
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