GATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors

Encouraging clinical results using immune checkpoint therapies to target the PD-1 axis in a variety of cancer types have paved the way for new immune therapy trials in brain tumor patients. However, the molecular mechanisms that regulate expression of the PD-1 pathway ligands, PD-L1 and PD-L2, remai...

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Publicado no:Sci Rep
Main Authors: Fu, Yujie, Liu, Connor J., Kobayashi, Dale K., Johanns, Tanner M., Bowman-Kirigin, Jay A., Schaettler, Maximilian O., Mao, Diane D., Bender, Diane, Kelley, Diane G., Uppaluri, Ravindra, Bi, Wenya Linda, Dunn, Ian F., Tao, Yu, Luo, Jingqin, Kim, Albert H., Dunn, Gavin P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271235/
https://ncbi.nlm.nih.gov/pubmed/32493985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65915-z
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