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Hair Cell Transduction Efficiency of Single- and Dual-AAV Serotypes in Adult Murine Cochleae
Gene delivery is a key component for the treatment of genetic hearing loss. To date, a myriad of adeno-associated virus (AAV) serotypes and surgical approaches have been employed to deliver transgenes to cochlear hair cells, but the efficacy of dual transduction remains unclear. Herein, we investiga...
Gespeichert in:
| Veröffentlicht in: | Mol Ther Methods Clin Dev |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Gene & Cell Therapy
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7270144/ https://ncbi.nlm.nih.gov/pubmed/32518805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.05.007 |
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