PDGFB-expressing mesenchymal stem cells improve human hematopoietic stem cell engraftment in immunodeficient mice

The bone marrow (BM) niche regulates multiple hematopoietic stem cell (HSC) processes. Clinical treatment for hematological malignancies by HSC transplantation often requires preconditioning via total body irradiation, which severely and irreversibly impairs the BM niche and HSC regeneration. Novel...

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Bibliografische gegevens
Gepubliceerd in:Bone Marrow Transplant
Hoofdauteurs: Yin, Xiuxiu, Hu, Linping, Zhang, Yawen, Zhu, Caiying, Cheng, Hui, Xie, Xiaowei, Shi, Ming, Zhu, Ping, Zhao, Xueying, Chen, Wanqiu, Zhang, Lu, Arakaki, Cameron, Hao, Sha, Wang, Mei, Cao, Wenbin, Ma, Shihui, Zhang, Xiao-Bing, Cheng, Tao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269905/
https://ncbi.nlm.nih.gov/pubmed/31804621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41409-019-0766-z
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