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Extracellular matrix, integrins, and focal adhesion signaling in polycystic kidney disease

In autosomal dominant polycystic kidney disease (ADPKD), the inexorable growth of numerous fluid-filled cysts leads to massively enlarged kidneys, renal interstitial damage, inflammation, and fibrosis, and progressive decline in kidney function. It has long been recognized that interstitial fibrosis...

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Bibliographic Details
Published in:Cell Signal
Main Authors: Zhang, Yan, Reif, Gail, Wallace, Darren P.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269823/
https://ncbi.nlm.nih.gov/pubmed/32311505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109646
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