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Oral immunotherapy tolerizes mice to enzyme replacement therapy for Morquio A syndrome
Immune response to therapeutic enzymes poses a detriment to patient safety and treatment outcome. Enzyme replacement therapy (ERT) is a standard therapeutic option for some types of mucopolysaccharidoses, including Morquio A syndrome caused by N-acetylgalactosamine-6-sulfate sulfatase (GALNS) defici...
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| Опубликовано в: : | J Clin Invest |
|---|---|
| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269574/ https://ncbi.nlm.nih.gov/pubmed/31743109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125607 |
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