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The surprising complexity of K(ATP) channel biology and of genetic diseases
The ATP-sensitive K(+) channel (K(ATP)) is formed by the association of four inwardly rectifying K(+) channel (Kir6.x) pore subunits with four sulphonylurea receptor (SUR) regulatory subunits. Kir6.x or SUR mutations result in K(ATP) channelopathies, which reflect the physiological roles of these ch...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269573/ https://ncbi.nlm.nih.gov/pubmed/32065592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI135759 |
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