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Clofazimine enhances the efficacy of BCG revaccination via stem cell-like memory T cells

Tuberculosis (TB) is one of the deadliest diseases, claiming ~2 million deaths annually worldwide. The majority of people in TB endemic regions are vaccinated with Bacillus Calmette Guerin (BCG), which is the only usable vaccine available. BCG is efficacious against meningeal and disseminated TB in...

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Vydáno v:PLoS Pathog
Hlavní autoři: Ahmad, Shaheer, Bhattacharya, Debapriya, Gupta, Neeta, Rawat, Varsha, Tousif, Sultan, Van Kaer, Luc, Das, Gobardhan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269335/
https://ncbi.nlm.nih.gov/pubmed/32437421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008356
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