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Inhibition of the CXCL12/CXCR4 axis prevents peri-urethral collagen accumulation and lower urinary tract dysfunction in vivo
BACKGROUND: Several studies show that prostatic fibrosis is associated with male lower urinary tract dysfunction (LUTD). Development of fibrosis is typically attributed to signaling through the TGFβ pathway, but our laboratory has demonstrated that in vitro treatment of human prostatic fibroblasts w...
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| Gepubliceerd in: | Prostate |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269149/ https://ncbi.nlm.nih.gov/pubmed/30811623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23781 |
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