CXCL12/CXCR4 Axis Activation Mediates Prostate Myofibroblast Phenoconversion through Non-Canonical EGFR/MEK/ERK Signaling

Benign prostate hyperplasia (BPH), an enlargement of the prostate common in aging in men, is associated with urinary voiding dysfunction manifest as Lower Urinary Tract Symptoms (LUTS). Although inflammation and abnormal smooth muscle contractions are known to play key roles in the development of LU...

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Udgivet i:PLoS One
Main Authors: Rodríguez-Nieves, José A., Patalano, Susan C., Almanza, Diego, Gharaee-Kermani, Mehrnaz, Macoska, Jill A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951124/
https://ncbi.nlm.nih.gov/pubmed/27434301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159490
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