Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL-34 and SCF in Amyotrophic Lateral Sclerosis

Distal axonopathy is a recognized pathological feature of amyotrophic lateral sclerosis (ALS). In the peripheral nerves of ALS patients, motor axon loss elicits a Wallerian-like degeneration characterized by denervated Schwann cells (SCs) together with immune cell infiltration. However, the pathogen...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Trias, Emiliano, Kovacs, Mariángeles, King, Peter H., Si, Ying, Kwon, Yuri, Varela, Valentina, Ibarburu, Sofía, Moura, Ivan C., Hermine, Olivier, Beckman, Joseph S., Barbeito, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269115/
https://ncbi.nlm.nih.gov/pubmed/31859421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23768
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