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Detecting Shared Genetic Architecture Among Multiple Phenotypes by Hierarchical Clustering of Gene-Level Association Statistics

Emerging large-scale biobanks pairing genotype data with phenotype data present new opportunities to prioritize shared genetic associations across multiple phenotypes for molecular validation. Past research, by our group and others, has shown gene-level tests of association produce biologically inte...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: McGuirl, Melissa R., Smith, Samuel Pattillo, Sandstede, Björn, Ramachandran, Sohini
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268989/
https://ncbi.nlm.nih.gov/pubmed/32245788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303096
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