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MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

BACKGROUND: The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogeneous tis...

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Bibliografske podrobnosti
izdano v:BMC Med Genomics
Main Authors: Friedrich, Stefanie, Barbulescu, Remus, Helleday, Thomas, Sonnhammer, Erik L. L.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268502/
https://ncbi.nlm.nih.gov/pubmed/32487140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00731-y
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