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MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

BACKGROUND: The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogeneous tis...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Med Genomics
Prif Awduron: Friedrich, Stefanie, Barbulescu, Remus, Helleday, Thomas, Sonnhammer, Erik L. L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268502/
https://ncbi.nlm.nih.gov/pubmed/32487140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00731-y
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