A multi-centre, pragmatic, three-arm, individually randomised, non-inferiority, open trial to compare immediate orally administered, immediate topically administered or delayed orally administered antibiotics for acute otitis media with discharge in children: The Runny Ear Study (REST): study protocol

BACKGROUND: Acute otitis media (AOM) is a common painful infection in children, with around 2.8 million cases presenting to primary care in England and Wales annually. Nearly all children who present to their general practitioner (GP) with AOM or AOM with discharge (AOMd) are treated with orally adm...

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Vydáno v:Trials
Hlavní autoři: Curtis, Kathryn, Moore, Michael, Cabral, Christie, Curcin, Vasa, Horwood, Jeremey, Morris, Richard, Prasad, Vibhore, Schilder, Anne, Turner, Nicholas, Wilkes, Scott, Hay, Alastair D., Taylor, Jodi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Study Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268414/
https://ncbi.nlm.nih.gov/pubmed/32493407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04419-7
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