A multi-centre, pragmatic, three-arm, individually randomised, non-inferiority, open trial to compare immediate orally administered, immediate topically administered or delayed orally administered antibiotics for acute otitis media with discharge in children: The Runny Ear Study (REST): study protocol

Abstract Background Acute otitis media (AOM) is a common painful infection in children, with around 2.8 million cases presenting to primary care in England and Wales annually. Nearly all children who present to their general practitioner (GP) with AOM or AOM with discharge (AOMd) are treated with or...

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Autori principali: Kathryn Curtis, Michael Moore, Christie Cabral, Vasa Curcin, Jeremey Horwood, Richard Morris, Vibhore Prasad, Anne Schilder, Nicholas Turner, Scott Wilkes, Alastair D. Hay, Jodi Taylor
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-06-01
Serie:Trials
Soggetti:
Acute otitis media
Primary care
Antibiotics
Paediatrics
Randomised controlled trial
Accesso online:http://link.springer.com/article/10.1186/s13063-020-04419-7
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