Single-cell DNA methylation sequencing reveals epigenetic alterations in mouse oocytes superovulated with different dosages of gonadotropins

BACKGROUND: Epigenetic abnormalities caused by superovulation have recently attracted increasing attention. Superovulation with exogenous hormones may prevent oocytes from establishing an appropriate epigenetic state, and this effect may extend to the methylation programming in preimplantation embry...

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Bibliografske podrobnosti
izdano v:Clin Epigenetics
Main Authors: Huo, Ying, Yan, Zhi Qiang, Yuan, Peng, Qin, Meng, Kuo, Ying, Li, Rong, Yan, Li Ying, Feng, Huai Liang, Qiao, Jie
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268365/
https://ncbi.nlm.nih.gov/pubmed/32487258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00866-w
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