Single-cell DNA methylation sequencing reveals epigenetic alterations in mouse oocytes superovulated with different dosages of gonadotropins

BACKGROUND: Epigenetic abnormalities caused by superovulation have recently attracted increasing attention. Superovulation with exogenous hormones may prevent oocytes from establishing an appropriate epigenetic state, and this effect may extend to the methylation programming in preimplantation embry...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: Huo, Ying, Yan, Zhi Qiang, Yuan, Peng, Qin, Meng, Kuo, Ying, Li, Rong, Yan, Li Ying, Feng, Huai Liang, Qiao, Jie
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268365/
https://ncbi.nlm.nih.gov/pubmed/32487258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00866-w
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