Single-cell DNA methylation sequencing reveals epigenetic alterations in mouse oocytes superovulated with different dosages of gonadotropins

BACKGROUND: Epigenetic abnormalities caused by superovulation have recently attracted increasing attention. Superovulation with exogenous hormones may prevent oocytes from establishing an appropriate epigenetic state, and this effect may extend to the methylation programming in preimplantation embry...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Huo, Ying, Yan, Zhi Qiang, Yuan, Peng, Qin, Meng, Kuo, Ying, Li, Rong, Yan, Li Ying, Feng, Huai Liang, Qiao, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268365/
https://ncbi.nlm.nih.gov/pubmed/32487258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00866-w
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