Single-cell DNA methylation sequencing reveals epigenetic alterations in mouse oocytes superovulated with different dosages of gonadotropins

BACKGROUND: Epigenetic abnormalities caused by superovulation have recently attracted increasing attention. Superovulation with exogenous hormones may prevent oocytes from establishing an appropriate epigenetic state, and this effect may extend to the methylation programming in preimplantation embry...

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Détails bibliographiques
Publié dans:Clin Epigenetics
Auteurs principaux: Huo, Ying, Yan, Zhi Qiang, Yuan, Peng, Qin, Meng, Kuo, Ying, Li, Rong, Yan, Li Ying, Feng, Huai Liang, Qiao, Jie
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268365/
https://ncbi.nlm.nih.gov/pubmed/32487258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00866-w
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