Association of circulating SLAMF7(+)Tfh1 cells with IgG4 levels in patients with IgG4-related disease

BACKGROUND: Follicular helper CD4(+) T (Tfh) cells have a critical role in IgG4 production by B cells in IgG4-related disease (IgG4-RD). Recent studies including ours showed that SLAMF7(+)CD4(+) T cells are an important pathological driver of IgG4-RD. In this study, we have sought to elucidate a rel...

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Dades bibliogràfiques
Publicat a:BMC Immunol
Autors principals: Higashioka, Kazuhiko, Ota, Yuri, Maehara, Takashi, Moriyama, Masafumi, Ayano, Masahiro, Mitoma, Hiroki, Akahoshi, Mitsuteru, Arinobu, Yojiro, Horiuchi, Takahiko, Nakamura, Seiji, Akashi, Koichi, Niiro, Hiroaki
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268355/
https://ncbi.nlm.nih.gov/pubmed/32487061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-020-00361-0
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