Airway microbial diversity is decreased in young children with cystic fibrosis compared to healthy controls but improved with CFTR modulation

BACKGROUND: Culture-independent next generation sequencing has identified diverse microbial communities within the cystic fibrosis (CF) airway. The study objective was to test for differences in the upper airway microbiome of children with CF and healthy controls and age-related differences in child...

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Bibliografiske detaljer
Udgivet i:Heliyon
Main Authors: Hahn, Andrea, Burrell, Aszia, Ansusinha, Emily, Peng, Diane, Chaney, Hollis, Sami, Iman, Perez, Geovanny F., Koumbourlis, Anastassios C., McCarter, Robert, Freishtat, Robert J., Crandall, Keith A., Zemanick, Edith T.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267737/
https://ncbi.nlm.nih.gov/pubmed/32514485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04104
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