Airway microbial diversity is decreased in young children with cystic fibrosis compared to healthy controls but improved with CFTR modulation

BACKGROUND: Culture-independent next generation sequencing has identified diverse microbial communities within the cystic fibrosis (CF) airway. The study objective was to test for differences in the upper airway microbiome of children with CF and healthy controls and age-related differences in child...

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Veröffentlicht in:Heliyon
Hauptverfasser: Hahn, Andrea, Burrell, Aszia, Ansusinha, Emily, Peng, Diane, Chaney, Hollis, Sami, Iman, Perez, Geovanny F., Koumbourlis, Anastassios C., McCarter, Robert, Freishtat, Robert J., Crandall, Keith A., Zemanick, Edith T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267737/
https://ncbi.nlm.nih.gov/pubmed/32514485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04104
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