2573. Impact of Anaerobic Antibacterial Spectrum on Cystic Fibrosis Lung Microbiome Diversity and Pulmonary Function

BACKGROUND: Next-generation sequencing has shown the cystic fibrosis (CF) lung microbiome to be a complex polymicrobial community. Anaerobic bacteria decrease in relative abundance with older age and disease progression, and may impact host inflammatory state. Persons with CF suffer from recurrent p...

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Published in:Open Forum Infect Dis
Main Authors: Jason. Bozzella, Michael, Chaney, Hollis, Sami, Iman, Perez, Geovanny, Koumbourlis, Anastassios, Bost, James, Freishtat, Robert, Crandall, Keith, Hahn, Andrea
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810446/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.2251
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