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IL-6 Blockade Reverses Bone Marrow Failure Induced by Human Acute Myeloid Leukemia

Most patients with acute myeloid leukemia (AML) die from complications arising from cytopenias resulting from bone marrow (BM) failure. The common presumption among physicians is that AML-induced BM failure is primarily due to overcrowding, yet BM failure is observed even with low burden of disease....

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Bibliografische gegevens
Gepubliceerd in:Sci Transl Med
Hoofdauteurs: Zhang, Tian Yi, Dutta, Ritika, Benard, Brooks, Zhao, Feifei, Yin, Raymond, Majeti, Ravindra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266679/
https://ncbi.nlm.nih.gov/pubmed/32269167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax5104
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