Complex context relationships between DNA methylation and accessibility, histone marks, and hTERT gene expression in acute promyelocytic leukemia cells: perspectives for all‐trans retinoic acid in cancer therapy

Telomerase (hTERT) reactivation and sustained expression is a key event in the process of cellular transformation. Therefore, the identification of the mechanisms regulating hTERT expression is of great interest for the development of new anticancer therapies. Although the epigenetic state of hTERT...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Garsuault, Delphine, Bouyer, Claire, Nguyen, Eric, Kandhari, Rohan, Prochazkova‐Carlotti, Martina, Chevret, Edith, Forgez, Patricia, Ségal‐Bendirdjian, Evelyne
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266276/
https://ncbi.nlm.nih.gov/pubmed/32239597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12681
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