Ablation of TRPV1+ Afferent Terminals by Capsaicin Mediates Long-Lasting Analgesia for Trigeminal Neuropathic Pain

Trigeminal neuropathic pain (TNP) is often resistant to current pharmacotherapy, and there is a pressing need to develop more efficacious treatments. Capsaicin is a pungent ingredient of chili peppers and specifically activates transient receptor potential vanilloid subtype 1 (TRPV1), a Ca(2+)-perme...

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Vydáno v:eNeuro
Hlavní autoři: Wang, Sheng, Bian, Chao, Yang, Jiale, Arora, Vipin, Gao, Yiwei, Wei, Feng, Chung, Man-Kyo
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2020
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Research Article: New Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266139/
https://ncbi.nlm.nih.gov/pubmed/32404326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0118-20.2020
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