Ablation of TRPV1+ Afferent Terminals by Capsaicin Mediates Long-Lasting Analgesia for Trigeminal Neuropathic Pain

Trigeminal neuropathic pain (TNP) is often resistant to current pharmacotherapy, and there is a pressing need to develop more efficacious treatments. Capsaicin is a pungent ingredient of chili peppers and specifically activates transient receptor potential vanilloid subtype 1 (TRPV1), a Ca(2+)-perme...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eNeuro
Prif Awduron: Wang, Sheng, Bian, Chao, Yang, Jiale, Arora, Vipin, Gao, Yiwei, Wei, Feng, Chung, Man-Kyo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2020
Pynciau:
Research Article: New Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266139/
https://ncbi.nlm.nih.gov/pubmed/32404326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0118-20.2020
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