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The Dynamics of Cytoplasmic mRNA Metabolism

For all but a few mRNAs, the dynamics of metabolism are unknown. Here, we developed an experimental and analytical framework for examining these dynamics for mRNAs from thousands of genes. mRNAs of mouse fibroblasts exit the nucleus with diverse intragenic and intergenic poly(A)-tail lengths. Once i...

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Dettagli Bibliografici
Pubblicato in:Mol Cell
Autori principali: Eisen, Timothy J., Eichhorn, Stephen W., Subtelny, Alexander O., Lin, Kathy S., McGeary, Sean E., Gupta, Sumeet, Bartel, David P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265681/
https://ncbi.nlm.nih.gov/pubmed/31902669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.12.005
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