Durable and controlled depletion of neutrophils in mice

Neutrophils are an essential part of the innate immune system. To study their importance, experimental studies often aim to deplete these cells, generally by injecting anti-Ly6G or anti-Gr1 antibodies. However, these approaches are only partially effective, transient or lack specificity. Here we rep...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Boivin, Gael, Faget, Julien, Ancey, Pierre-Benoit, Gkasti, Aspasia, Mussard, Julie, Engblom, Camilla, Pfirschke, Christina, Contat, Caroline, Pascual, Justine, Vazquez, Jessica, Bendriss-Vermare, Nathalie, Caux, Christophe, Vozenin, Marie-Catherine, Pittet, Mikael J., Gunzer, Matthias, Meylan, Etienne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265525/
https://ncbi.nlm.nih.gov/pubmed/32488020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16596-9
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