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A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts

ToxR is a transmembrane transcription factor that, together with its integral membrane periplasmic binding partner ToxS, is conserved across the Vibrionaceae family. In some pathogenic Vibrios, including V. parahaemolyticus and V. cholerae, ToxR is required for bile resistance and virulence, and Tox...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Midgett, Charles R., Swindell, Rachel A., Pellegrini, Maria, Jon Kull, F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265457/
https://ncbi.nlm.nih.gov/pubmed/32488093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66050-5
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