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A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
ToxR is a transmembrane transcription factor that, together with its integral membrane periplasmic binding partner ToxS, is conserved across the Vibrionaceae family. In some pathogenic Vibrios, including V. parahaemolyticus and V. cholerae, ToxR is required for bile resistance and virulence, and Tox...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7265457/ https://ncbi.nlm.nih.gov/pubmed/32488093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66050-5 |
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