Proteolysis of ToxR is controlled by cysteine‐thiol redox state and bile salts in Vibrio cholerae

In Vibrio cholerae, virulence gene expression is regulated by a transmembrane‐localized transcription factor complex designated as ToxRS. ToxR harbours two cysteines in the periplasmic domain that can form inter‐ and intramolecular disulfide bonds. In this study, we investigated the σ(E)‐dependent i...

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Bibliografiske detaljer
Udgivet i:Mol Microbiol
Main Authors: Lembke, Mareike, Pennetzdorfer, Nina, Tutz, Sarah, Koller, Michael, Vorkapic, Dina, Zhu, Jun, Schild, Stefan, Reidl, Joachim
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242745/
https://ncbi.nlm.nih.gov/pubmed/30218472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14125
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