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Proteolysis of Virulence Regulator ToxR Is Associated with Entry of Vibrio cholerae into a Dormant State

Vibrio cholerae O1 is a natural inhabitant of aquatic environments and causes the diarrheal disease, cholera. Two of its primary virulence regulators, TcpP and ToxR, are localized in the inner membrane. TcpP is encoded on the Vibrio Pathogenicity Island (VPI), a horizontally acquired mobile genetic...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Almagro-Moreno, Salvador, Kim, Tae K., Skorupski, Karen, Taylor, Ronald K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388833/
https://ncbi.nlm.nih.gov/pubmed/25849031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005145
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