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Polarized sorting of Patched enables cytoneme‐mediated Hedgehog reception in the Drosophila wing disc

Hedgehog (Hh) signal molecules play a fundamental role in development, adult stem cell maintenance and cancer. Hh can signal at a distance, and we have proposed that its graded distribution across Drosophila epithelia is mediated by filopodia‐like structures called cytonemes. Hh reception by Patched...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: González‐Méndez, Laura, Gradilla, Ana‐Citlali, Sánchez‐Hernández, David, González, Esperanza, Aguirre‐Tamaral, Adrián, Jiménez‐Jiménez, Carlos, Guerra, Milagros, Aguilar, Gustavo, Andrés, Germán, Falcón‐Pérez, Juan M, Guerrero, Isabel
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265244/
https://ncbi.nlm.nih.gov/pubmed/32311148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103629
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