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miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway

BRD4, a member of the bromodomain and extra-terminal domain (BET) protein family, plays a role in the organization of super-enhancers and transcriptional activation of oncogenes in cancer and is recognized as a promising target for cancer therapy. microRNAs (miRNAs), endogenous small noncoding RNAs,...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Takagawa, Yuki, Gen, Yasuyuki, Muramatsu, Tomoki, Tanimoto, Kousuke, Inoue, Jun, Harada, Hiroyuki, Inazawa, Johji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264468/
https://ncbi.nlm.nih.gov/pubmed/32320642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.04.001
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