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miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer

The epithelial-mesenchymal transition (EMT) contributes to various processes in cancer progression, such as metastasis and drug resistance. Since we have already established a cell-based reporter system for identifying EMT-suppressive microRNAs (miRNAs) in the pancreatic cancer cell line Panc1, we p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hiramoto, Hidekazu, Muramatsu, Tomoki, Ichikawa, Daisuke, Tanimoto, Kousuke, Yasukawa, Satoru, Otsuji, Eigo, Inazawa, Johji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479822/
https://ncbi.nlm.nih.gov/pubmed/28638102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04191-w
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