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MeCP2 facilitates breast cancer growth via promoting ubiquitination-mediated P53 degradation by inhibiting RPL5/RPL11 transcription

Methyl-CpG-binding protein 2 (MeCP2) facilitates the carcinogenesis and progression of several types of cancer. However, its role in breast cancer and the relevant molecular mechanism remain largely unclear. In this study, analysis of the Cancer Genome Atlas (TCGA) data that MeCP2 expression was sig...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Tong, DongDong, Zhang, Jing, Wang, XiaoFei, Li, Qian, Liu, Li Ying, Yang, Juan, Guo, Bo, Ni, Lei, Zhao, LingYu, Huang, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264296/
https://ncbi.nlm.nih.gov/pubmed/32483207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-0239-7
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