Polyporus Polysaccharide Ameliorates Bleomycin-Induced Pulmonary Fibrosis by Suppressing Myofibroblast Differentiation via TGF-β/Smad2/3 Pathway

Pulmonary fibrosis is a major cause of morbidity and mortality in systemic sclerosis (SSc) with no effective medication. Polyporus polysaccharide (PPS), extracted from Chinese herbs, has immune regulation, anticancer, antioxidant and antiinflammatory activities. This study aims to investigate antifi...

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Publicado en:Front Pharmacol
Autores principales: Jiang, Jintao, Wang, Fang, Luo, Aishu, Lin, Shiyu, Feng, Xiaoke, Yan, Wei, Shi, Yumeng, Zhang, Qian, Gu, Xin, Cui, Guoliang, Wang, Jianan, Wang, Lei, Zhang, Qiande, Tan, Wenfeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264095/
https://ncbi.nlm.nih.gov/pubmed/32528292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00767
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