NormQ: RNASeq normalization based on RT-qPCR derived size factors

The merit of RNASeq data relies heavily on correct normalization. However, most methods assume that the majority of transcripts show no differential expression between conditions. This assumption may not always be correct, especially when one condition results in overexpression. We present a new met...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Main Authors: Naraine, Ravindra, Abaffy, Pavel, Sidova, Monika, Tomankova, Silvie, Pocherniaieva, Kseniia, Smolik, Ondrej, Kubista, Mikael, Psenicka, Martin, Sindelka, Radek
Formato: Artigo
Idioma:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264052/
https://ncbi.nlm.nih.gov/pubmed/32514328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.05.010
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