NormQ: RNASeq normalization based on RT-qPCR derived size factors

The merit of RNASeq data relies heavily on correct normalization. However, most methods assume that the majority of transcripts show no differential expression between conditions. This assumption may not always be correct, especially when one condition results in overexpression. We present a new met...

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Veröffentlicht in:Comput Struct Biotechnol J
Hauptverfasser: Naraine, Ravindra, Abaffy, Pavel, Sidova, Monika, Tomankova, Silvie, Pocherniaieva, Kseniia, Smolik, Ondrej, Kubista, Mikael, Psenicka, Martin, Sindelka, Radek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Research Network of Computational and Structural Biotechnology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264052/
https://ncbi.nlm.nih.gov/pubmed/32514328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.05.010
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