NormQ: RNASeq normalization based on RT-qPCR derived size factors

The merit of RNASeq data relies heavily on correct normalization. However, most methods assume that the majority of transcripts show no differential expression between conditions. This assumption may not always be correct, especially when one condition results in overexpression. We present a new met...

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Dettagli Bibliografici
Pubblicato in:Comput Struct Biotechnol J
Autori principali: Naraine, Ravindra, Abaffy, Pavel, Sidova, Monika, Tomankova, Silvie, Pocherniaieva, Kseniia, Smolik, Ondrej, Kubista, Mikael, Psenicka, Martin, Sindelka, Radek
Natura: Artigo
Lingua:Inglês
Pubblicazione: Research Network of Computational and Structural Biotechnology 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264052/
https://ncbi.nlm.nih.gov/pubmed/32514328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.05.010
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