Separating dopamine D(2) and D(3) receptor sources of [(11)C]-(+)-PHNO binding potential: independent component analysis of competitive binding

Development of medications selective for dopamine D(2) or D(3) receptors is an active area of research in numerous neuropsychiatric disorders including addiction and Parkinson’s disease. The positron emission tomography (PET) radiotracer [(11)C]-(+)-PHNO, an agonist that binds with high affinity to...

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Bibliografiske detaljer
Udgivet i:	Neuroimage
Main Authors:	Smart, Kelly, Gallezot, Jean-Dominique, Nabulsi, Nabeel, Labaree, David, Zheng, Ming-Qiang, Huang, Yiyun, Carson, Richard E., Hillmer, Ansel T., Worhunsky, Patrick D.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2020
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7263955/ https://ncbi.nlm.nih.gov/pubmed/32201327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2020.116762
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Separating dopamine D(2) and D(3) receptor sources of [(11)C]-(+)-PHNO binding potential: independent component analysis of competitive binding

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