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Olanzapine-induced liver injury in mice: aggravation by high-fat diet and protection with sulforaphane

Olanzapine is effective to treat for schizophrenia and other mood disorders, but limited by side effects such as weight gain, dyslipidemia, and liver injury. Obesity in the US is at epidemic levels, and is a significant risk factor for drug-induced liver injury. Obesity incidence in the psychiatric...

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Detalhes bibliográficos
Publicado no:J Nutr Biochem
Main Authors: Isaacson, Robin H., Beier, Juliane I., Khoo, Nicholas KH, Freeman, Bruce A., Freyberg, Zachary, Arteel, Gavin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263947/
https://ncbi.nlm.nih.gov/pubmed/32388251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2020.108399
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