ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells

Deoxyribonucleic acid (DNA) damage response (DDR) is the fundamental cellular response for maintaining genomic integrity and suppressing tumorigenesis. The activation of ataxia telangiectasia-mutated (ATM) kinase is central to DNA double-strand break (DSB) for maintaining host-genome integrity in ma...

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Vydáno v:PLoS Pathog
Hlavní autoři: Ren, Shanhui, Ur Rehman, Zaib, Gao, Bo, Yang, Zengqi, Zhou, Jiyong, Meng, Chunchun, Song, Cuiping, Nair, Venugopal, Sun, Yingjie, Ding, Chan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263568/
https://ncbi.nlm.nih.gov/pubmed/32479542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008514
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