Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase

The ongoing Corona Virus Disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has emphasized the urgent need for antiviral therapeutics. The viral RNA-dependent-RNA-polymerase (RdRp) is a promising target with polymerase inhibitors successfully us...

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Foilsithe in:bioRxiv
Main Authors: Shannon, A., Selisko, B., Le, NTT, Huchting, J., Touret, F., Piorkowski, G., Fattorini, V., Ferron, F., Decroly, E., Meier, C, Coutard, B., Peersen, O., Canard, B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263509/
https://ncbi.nlm.nih.gov/pubmed/32511380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.15.098731
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